KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFHX4
All Species:
13.03
Human Site:
S494
Identified Species:
31.85
UniProt:
Q86UP3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UP3
NP_078997.3
3567
393730
S494
V
L
G
E
L
T
D
S
I
G
N
K
D
F
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089817
3156
348587
R274
G
C
V
S
D
G
K
R
K
P
V
L
M
C
F
Dog
Lupus familis
XP_853266
3452
379865
S494
A
L
G
E
L
T
D
S
I
G
N
K
D
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN2
3550
392304
S493
V
L
G
E
L
T
D
S
I
G
N
K
D
F
P
Rat
Rattus norvegicus
XP_226964
3593
395739
I495
V
G
E
L
T
D
S
I
G
N
K
D
F
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509863
3710
407348
K523
V
A
G
S
S
S
K
K
D
L
A
L
S
N
Q
Chicken
Gallus gallus
O73590
3573
394529
S494
V
L
G
E
L
A
D
S
I
G
S
K
D
F
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684360
2686
299027
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393785
2962
326678
A80
S
L
V
F
P
Q
I
A
S
A
Y
Y
V
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798150
3296
366823
I414
T
P
N
T
T
T
T
I
S
T
T
S
E
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.1
90.4
N.A.
90.8
91.8
N.A.
55.3
90.2
N.A.
52.6
N.A.
N.A.
21.1
N.A.
26
Protein Similarity:
100
N.A.
87.6
92.4
N.A.
94.1
94.9
N.A.
68.1
94
N.A.
61.7
N.A.
N.A.
36.2
N.A.
41.1
P-Site Identity:
100
N.A.
0
93.3
N.A.
100
6.6
N.A.
13.3
86.6
N.A.
0
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
0
93.3
N.A.
100
6.6
N.A.
20
93.3
N.A.
0
N.A.
N.A.
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
10
0
10
0
10
10
0
0
0
10
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
10
10
40
0
10
0
0
10
40
10
0
% D
% Glu:
0
0
10
40
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
10
40
10
% F
% Gly:
10
10
50
0
0
10
0
0
10
40
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
20
40
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
20
10
10
0
10
40
0
0
0
% K
% Leu:
0
50
0
10
40
0
0
0
0
10
0
20
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
30
0
0
10
0
% N
% Pro:
0
10
0
0
10
0
0
0
0
10
0
0
0
10
40
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% R
% Ser:
10
0
0
20
10
10
10
40
20
0
10
10
10
10
0
% S
% Thr:
10
0
0
10
20
40
10
0
0
10
10
0
0
0
0
% T
% Val:
50
0
20
0
0
0
0
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _